About

Hi there, I’m Claire!

I am an early career scientist in bioinformatics in the Stem Cell Translation Laboratory (SCTL) and the Informatics department at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH). As the sole bioinformatician in SCTL, I build data pipelines for analysis of high-throughput single cell RNASeq, bulk RNASeq, proteomics, and other -omics data. This group at NCATS aims to be at the forefront of iPSC research to rigorously answer questions such as:

  • What are the ideal culturing conditions for iPSC differentiation?
  • How transcriptionally heterogenous are our differentiated cell types, including neural progenitors? Which transcription factors are strong determinants for cell fate?
  • How can you aggregate single cell RNA from multiple sequencing platforms, while applying best quality control practices?
  • How can we best share our data and findings with the public?

Previously I was a research data analyst at Johns Hopkins University in the Division of Allergy and Clinical Immunology, also known as the Data Analysis Core. Before that I completed a Master’s of Science at Northwestern University. I have experience with whole genome sequencing data, genome annotation, and development of new bioinformatics software where there is need in my lab and broadly in the science community. If you would like a copy of my CV or to just get in touch, you can contact me at malleyce [at] nih [dot] gov.

Goals

  • Potentially pursue PhD in computer science or bioinformatics in part because I would like to develop my software development skills
  • Learn new functional programming languages and bio-tools in the meantime
  • Disseminate the SCTL’s research findings broadly
  • Publish!

Personal interests

  • Programming. I use Perl, R, bash, Python, and SAS. I am fluent in R and have grown to love the language.
  • Electronic & experimental music.
  • Digital art. I create abstract and photorealistic pieces.

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